Product Description
TNFSF14 Antibody | 18-439 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant protein of human TNFSF14
Research Area: Chemokines & Cytokines, Immunology, Innate Immunity
Tested Application: WB
Application: WB: 1:1000 - 1:2000
Specificiy: N/A
Positive Control 1: Raji
Positive Control 2: LO2
Positive Control 3: A-549
Positive Control 4: 293T
Positive Control 5: THP-1
Positive Control 6: N/A
Molecular Weight: Observed: 30kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: tumor necrosis factor superfamily member LIGHT, tumor necrosis factor receptor-like 2, tumor necrosis factor ligand superfamily, member 14, ligand for herpesvirus entry mediator, herpesvirus entry mediator A, delta transmembrane LIGHT, TR2, LTg, LIGHT, HVEML, CD258, tumor necrosis factor (ligand) superfamily, TNFSF14, UNQ391/PRO726
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM) . This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.