Product Description
BTK Antibody [9D11A9] | 13-186 | ProSci
Host: Mouse
Reactivity: Human, Mouse
Homology: N/A
Immunogen: Recombinant protein of human BTK
Research Area: Apoptosis, Cell Cycle, Immunology, Innate Immunity, Signal Transduction
Tested Application: WB, IP
Application: WB: 1:500 - 1:2000
IP: 1:20 - 1:50
Specificiy: N/A
Positive Control 1: K-562
Positive Control 2: Raji
Positive Control 3: THP-1
Positive Control 4: Mouse spleen
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 80kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Monoclonal
Clone: [9D11A9]
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: BTK Antibody: AT, ATK, BPK, XLA, IMD1, AGMX1, PSCTK1, Tyrosine-protein kinase BTK, Agammaglobulinemia tyrosine kinase
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.