Product Description
CD278 Antibody [ISA-3] (PE) | 76-967 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: N/A
Research Area: Immunology
Tested Application: Flow
Application: N/A
Specificiy: The ISA-3 monoclonal antibody specifically reacts with human CD278 or Inducible COStimulatory molecule (ICOS) , a 47-60 kDA homodimeric glycoprotein also known as H4, AILIM, and CRP-1.
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality: Monoclonal
Clone: ISA-3
Isotype: Mouse IgG1, kappa
Conjugate: PE
Physical State: liquid
Buffer: Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration: batch dependent
Storage Condition: The product should be stored undiluted at 4˚C and should be protected from prolonged exposure to light. Do not freeze.
Alternate Name: AILIM, CD278, CVID1, ICOS
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The ISA-3 monoclonal antibody specifically reacts with human CD278 or Inducible COStimulatory molecule (ICOS) , a 47-60 kDA homodimeric glycoprotein also known as H4, AILIM, and CRP-1. It is expressed on activated T cells and a group of thymocytes and is involved in the proliferation, activation, and cytokine production of T cells. When plate-bound, the ISA-3 antibody induces the production of IL-4, 5, 10 in T cells.