Product Description
CD279 Antibody [MIH4] (FITC) | 76-974 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: N/A
Research Area: Immunology, Apoptosis
Tested Application: Flow
Application: N/A
Specificiy: The MIH4 monoclonal antibody specifically reacts with human Programmed death-1 (PD-1 or CD279) , a 50-55 kDA glycoprotein.
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality: Monoclonal
Clone: MIH4
Isotype: Mouse IgG1, kappa
Conjugate: FITC
Physical State: liquid
Buffer: Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration: batch dependent
Storage Condition: The product should be stored undiluted at 4˚C and should be protected from prolonged exposure to light. Do not freeze.
Alternate Name: PD1, PD-1, CD279, SLEB2, hPD-1, hPD-l, hSLE1, PDCD1
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The MIH4 monoclonal antibody specifically reacts with human Programmed death-1 (PD-1 or CD279) , a 50-55 kDA glycoprotein. It is expressed on mainly on activated B, T, and myeloid cells. Within the cytoplasmic region, PD-1 contains an Immunoreceptor tyrosine-based inhibitory motif (ITIM) and seems to regulate peripheral tolerance. The lack or mutation of CD279 is linked to autoimmune disorders.