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![CD283 Antibody [TLR3.7] (PE)](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/556153/765172/porsci_lo__79508.1648973713__44648.1649086729.png?c=2 "CD283 Antibody [TLR3.7] (PE)")
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Product Description
CD283 Antibody [TLR3.7] (PE) | 76-956 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: N/A
Research Area: Innate Immunity
Tested Application: Flow
Application: N/A
Specificiy: The TLR3.7 monoclonal antibody specifically reacts with human CD283 (TLR3) , a type I transmembrane signaling receptor containing IL-1 receptor like intracellular domain and leucine-rich repeats (LRR) in the extracellular domain.
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality: Monoclonal
Clone: TLR3.7
Isotype: Mouse IgG1, kappa
Conjugate: PE
Physical State: liquid
Buffer: Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration: batch dependent
Storage Condition: The product should be stored undiluted at 4˚C and should be protected from prolonged exposure to light. Do not freeze.
Alternate Name: CD283, IIAE2, TLR3
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The TLR3.7 monoclonal antibody specifically reacts with human CD283 (TLR3) , a type I transmembrane signaling receptor containing IL-1 receptor like intracellular domain and leucine-rich repeats (LRR) in the extracellular domain. It is expressed by dendritic cells and recognize double-stranded RNA and polyinosine-polycytidylic acid. Upon ligand binding, CD283 induces type I interferon production and activation of the nuclear factor kappa-light-chain-enhancer of activated B cells complex (NF-κB) .
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