Product Description
CD3 Antibody [Hit3a] | 76-213 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: N/A
Research Area: Immunology, Functional Assays
Tested Application: Flow, Func, IHC, IP
Application: N/A
Specificiy: The Hit3a monoclonal antibody specifically reacts with the epsilon chain of the CD3/T lymphocyte antigen receptor complex.
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: The monoclonal antibody was purified utilizing affinity chromatography.
Clonality: Monoclonal
Clone: Hit3a
Isotype: Mouse IgG2a, kappa
Conjugate: Unconjugated
Physical State: liquid
Buffer: Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration: batch dependent
Storage Condition: The product should be stored undiluted at 4˚C . Do not freeze.
Alternate Name: T3E, TCRE, IMD18, CD3E
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The Hit3a monoclonal antibody specifically reacts with the epsilon chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.The HIT3a antibody cross-links with the TCR complex, initiating the cellular activation and proliferation, but it cannot be used for intracellular CD3 staining, as it is able to stain only the surface CD3 complex.