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![CD37 Antibody [IPO-24]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/575342/811925/porsci_lo__79508.1648973713__99833.1649091897.png?c=2 "CD37 Antibody [IPO-24]")
![CD37 Antibody [IPO-24]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/575342/811925/porsci_lo__79508.1648973713__99833.1649091897.png?c=2 "CD37 Antibody [IPO-24]")
Product Description
CD37 Antibody [IPO-24] | 33-505 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: Spleen cells from a patient with hairy cell leukemia were used as the immunogen for the CD37 antibody.
Research Area: Immunology
Tested Application: WB, Func, Flow, IF
Application: Functional Activity (Order SAF formulation)
Flow Cytometry: 0.5-1 ug/million cells in 0.1ml
Immunofluorescence: 0.5-1 ug/ml
Optimal dilution of the CD37 antibody should be determined by the researcher.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Protein G affinity chromatography
Clonality: Monoclonal
Clone: IPO-24
Isotype: IgG2b, kappa
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration: 0.2 mg/mL
Storage Condition: Aliquot and Store at 2-8˚C. Avoid freez-thaw cycles.
Alternate Name: Leukocyte antigen CD37, Tetraspanin-26, Tspan-26, CD37, CD37, TSPAN26
User Note: Optimal dilutions for each application to be determined by the researcher
BACKGROUND: Recognizes a protein of 33-55kDa, identified as CD37 (Workshop V; Code CD37.7) . CD37 is strongly expressed on normal and neoplastic mature (sIg+) B-lymphocytes. In B-cell ontogeny, CD37 appears after the pre-B-cell stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells.1 CD37 is also present, at low densities, on resting and activated T cells, neutrophils, monocytes, and some myelomonocytic leukemia cells. It is absent from platelets, erythrocytes. CD37 is a member of a family of tetraspan transmembrane proteins, including CD9, CD53, CD63, CD81, and CD82. It associates other tetraspan transmembrane proteins and MHC class II molecules to form a large complex at the surface of B cells and play a role in signal transduction. CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies like B-cell chronic lymphocytic leukemia (B-CLL) , hairy cell leukemia (HCL) , and all types of B-cell non-Hodgkin'' lymphoma (B-NHL) .
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