Product Description
CDK1 Antibody [8C3G11] | 13-010 | ProSci
Host: Mouse
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant protein of human CDK1
Research Area: Apoptosis, Cell Cycle, Immunology, Neuroscience, Signal Transduction
Tested Application: WB, ICC
Application: WB: 1:100 - 1:200
ICC: 1:50 - 1:100
Specificiy: N/A
Positive Control 1: Jurkat
Positive Control 2: A-549
Positive Control 3: K-562
Positive Control 4: HeLa
Positive Control 5: MCF7
Positive Control 6: A-431
Molecular Weight: Observed: 37kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Monoclonal
Clone: [8C3G11]
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: CDC2, CDC28A, CDK1, DKFZp686L20222, MGC111195, CDC2, P34CDC2
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF) , which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.