Product Description
CHD4 Antibody [4D10G6] | 23-969 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: Recombinant protein of human CHD4
Research Area: Immunology
Tested Application: WB
Application: WB: 1:500 - 1:1000
Specificiy: N/A
Positive Control 1: 293T
Positive Control 2: HL-60
Positive Control 3: Jurkat
Positive Control 4: K-562
Positive Control 5: A375
Positive Control 6: LO2
Molecular Weight: Observed: 300kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Monoclonal
Clone: [4D10G6]
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: CHD4, ATP-dependent helicase CHD4, CHD-4, Mi-2b, Mi2-BETA
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms.