Product Description
CKit Antibody [8D7B4 / 8D7D4 / 7H6B2 / 7H6B12] | 32-138 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: Ni-NTA purified truncated recombinant C-kit expressed in E. Coli strain BL21 (DE3) .
Research Area: Innate Immunity
Tested Application: E
Application: Dilution
ELISA:Propose dilution 1:10, 000
Determining optimal working dilutions by titration test.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Antibody is purified by protein A affinity chromatography.
Clonality: Monoclonal
Clone: 8D7B4 / 8D7D4 / 7H6B2 / 7H6B12
Isotype: IgG1
Conjugate: Unconjugated
Physical State: N/A
Buffer: Ascitic fluid containing 0.03% sodium azide.
Concentration: N/A
Storage Condition: C-Kit monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Alternate Name: SCFR, Piebald trait protein, SCFR, PBT, C-Kit, CD117
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: C-kit (CD117, 145 kDa) functions as a tyrosine kinase receptor which becomes activated upon binding of its ligand SCF (stem-cell factor) , the C-kit gene encodes the human homolog of the proto-oncogene c-kit. which was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor) . Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.