Product Description
FGF-23 Antibody [FGF23/638] | 33-227 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: A recombinant human FGF-23 protein was used as the immunogen for this antibody.
Research Area: Obesity
Tested Application: E, Func
Application: ELISA: order BSA-free format for coating
Functional testing: order BSA/azide-free format
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the FGF-23 antibody to be titered up or down for optimal performance.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Protein G purified FGF-23 antibody
Clonality: Monoclonal
Clone: FGF23/638
Isotype: IgG1, kappa
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration: 0.2 mg/mL
Storage Condition: Aliquot and Store at 2-8˚C. Avoid freez-thaw cycles.
Alternate Name: Fibroblast Growth Factor 23; Tumor-derived Hypophosphatemia-inducing Factor
User Note: Optimal dilutions for each application to be determined by the researcher
BACKGROUND: Fibroblast growth factor-1 (FGF-1) , also designated acidic FGF, and fibroblast growth factor-2 (FGF-2) , also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Additional members of the family include the oncogenes FGF3 (Int2) and FGF4 (hst/Kaposi) , FGF5, FGF6, FGF7 (KGF) , FGF8 (AIGF) , FGF9 (GAF) and FGF10 through FGF-23. Members of the family share 30-55% amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in trans- fected cells. Cellular receptors for FGFs are members of a second multigene family, including four tyrosine kinases designated Flg (FGFR-1) , Bek (FGFR-L) , TKF and FGFR-3.