Product Description
IGF1 Antibody [M23] | 33-144 | ProSci
Host: Mouse
Reactivity: Human, Mouse, Rat, Rabbit
Homology: N/A
Immunogen: Purified human IGF1 protein was used as the immunogen for this antibody.
Research Area: Immunology
Tested Application: Flow, IF, Inhibition
Application: Flow Cytometry: 0.5-1 ug/million cells
IF: 1-2 ug/ml
Functional Activity: In vitro inhibition of IGF1 Activity; order BSA/azide free format
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Protein G affinity chromatography
Clonality: Monoclonal
Clone: M23
Isotype: IgG1, kappa
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration: 0.2 mg/mL
Storage Condition: Aliquot and Store at 2-8˚C. Avoid freez-thaw cycles.
Alternate Name: IGF1, OTTHUMP00000195084, insulin-like growth factor 1 (somatomedin C) , insulin-like growth factor 1, IGFI, IGF1A, IBP1
User Note: Optimal dilutions for each application to be determined by the researcher
BACKGROUND: This antibody is specific to IGF1 (Insulin like Growth Factor 1) and shows minimal cross-reaction with IGF11, Proinsulin, MSF, and Insulin. IGF1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF1B while isoform 2 is known as IGF1A. IGF1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of the IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.