Product Description
LTF Antibody [3D8A7] | 16-354 | ProSci
Host: Mouse
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant protein of human LTF
Research Area: Apoptosis, Cancer, Cell Cycle
Tested Application: WB, IHC, IF
Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:20 - 1:50
Specificiy: N/A
Positive Control 1: K-562
Positive Control 2: HeLa
Positive Control 3: 293T
Positive Control 4: Mouse lung
Positive Control 5: Mouse spleen
Positive Control 6: Rat lung
Molecular Weight: Observed: 68kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Monoclonal
Clone: [3D8A7]
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, pH7.3.
Concentration: N/A
Storage Condition: Store at 4˚C. Avoid freeze / thaw cycles.
Alternate Name: LTF, lactotransferrin, GIG12, HLF2, LF, growth-inhibiting protein 12, lactoferrin, neutrophil lactoferrin, talalactoferrin
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Antimicrobial, antiviral, antifungal and antiparasitic activity has been found for this protein and its peptides. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.