Product Description
MAPK11 Antibody [4H6H6] | 32-190 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: Purified truncated recombinant MAPK11 (aa251-363) -Trx fusion protein is expressed in E. Coli strain BL21 (DE3) .
Research Area: Signal Transduction
Tested Application: E, WB
Application: Western Blot:1:500 - 1:2, 000
ELISA:Propose dilution 1:10, 000.
Determining optimal working dilutions by titration test.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: 4H6H6
Isotype: IgG1
Conjugate: Unconjugated
Physical State: N/A
Buffer: Ascitic fluid containing 0.03% sodium azide.
Concentration: N/A
Storage Condition: MAPK11 monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Alternate Name: P38B, SAPK2, p38-2, PRKM11, SAPK2B, p38Beta, P38BETA2
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Mitogen-activated protein kinase 11.The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs) , preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.