Product Description
Ribosomal Protein S3 Antibody [RP159-1] | 36-050 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: Recombinant human ribosomal protein S3.
Research Area: Innate Immunity
Tested Application: E, WB
Application: ELISA: (direct or indirect: 1:500-1:5, 000) . Western blot: (1:500-1:5, 000 using ECL. Suggested blocking and dilution buffer is PBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at rooom temperature) . Optimal conditions should be determined individually for each application.
Specificiy: Recognizes human ribosomal protein S3. Detects a band of ~32kDa by Western blot.
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: RP159-1
Isotype: IgG1, kappa
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration: 1 mg/ml
Storage Condition: Stable for at least 1 year after receipt when stored at -20˚C.
Alternate Name: 40S Ribosomal Protein S3; IMR-90 Ribosomal Protein S3; RPS3
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: RpS3 is a component of the 40S ribosomal subunit and is an an essential but previously unkown subunit of NF-kappaB involved in the regulation of key genes in rapid cellular activation responses. RpS3 interacts with nm23-H1. The expression of rpS3 reduces the secretion of MMP-9 and the invasive metastatic potential in HT1080 cells. The phosphorylated ERK is reduced by the expression of rpS3.