Product Description
RUNX3 Antibody [RNX864] | 33-059 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: A RUNX3 recombinant protein fragment was used as the immunogen for this antibody.
Research Area: Other
Tested Application: WB
Application: Western blot: 2-4 ug/ml
Provided assay concentrations are suggestions only, RUNX3 antibody titration may be required for optimal results.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Protein G Affinity Chromatography
Clonality: Monoclonal
Clone: RNX864
Isotype: IgG1, kappa
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration: 0.5 mg/mL
Storage Condition: Aliquot and Store at -20˚C. Avoid freez-thaw cycles.
Alternate Name: Runt-related transcription factor 3, Acute myeloid leukemia 2 protein, Core-binding factor subunit alpha-3, CBF-alpha-3, Oncogene AML-2, Polyomavirus enhancer-binding protein 2 alpha C subunit, PEA2-alpha C, PEBP2-alpha C, SL3-3 enhancer factor 1 alpha C subunit, SL3/AKV core-binding factor alpha C subunit, RUNX3, AML2, CBFA3, PEBP2A3
User Note: Optimal dilutions for each application to be determined by the researcher
BACKGROUND: The Runt family of transcription factors is involved in both normal cell development and carcinogenesis. Runt-related transcription factor 3 has been shown to be a tumor suppressor. Hypermethylation and mislocalization of the protein to the cytoplasm leads to low levels of RUNX3 and increased proliferation of breast and gastric tumor cells.