Product Description
Survivin Antibody [2H5H2] | 32-222 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: Purified full-length recombinant Survivin-His is expressed in E.Coli strain BL21 (DE3) .The antigen is soluble.
Research Area: Apoptosis, Growth Factors, Neuroscience, Cancer
Tested Application: E, WB
Application: Western Blot:1:500 - 1:2, 000
ELISA:Propose dilution 1:10, 000.
Determining optimal working dilutions by titration test.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: 2H5H2
Isotype: IgG1
Conjugate: Unconjugated
Physical State: N/A
Buffer: Ascitic fluid containing 0.03% sodium azide.
Concentration: N/A
Storage Condition: Survivin monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Alternate Name: API4, IAP4, Apoptosis inhibitor 4API4, EPR-1
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Baculoviral IAP repeat-containing 5 (survivin) .This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined.