Product Description
TGFbeta1 Antibody [4F9C10] | 32-224 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: Ni-NTA purified truncated recombinant TGFbeta1 expressed in E. Coli strain BL21 (DE3) .
Research Area: Growth Factors, Growth Factors
Tested Application: E, WB
Application: Western Blot:1:500 - 1:2, 000
ELISA:Propose dilution 1:10, 000.
Determining optimal working dilutions by titration test.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: 4F9C10
Isotype: IgG2a
Conjugate: Unconjugated
Physical State: N/A
Buffer: Ascitic fluid containing 0.03% sodium azide.
Concentration: N/A
Storage Condition: TGF beta1 monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Alternate Name: TGFBTGF-beta-1, CED, LAP, DPD1, TGFB, TGFbeta
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: TGF beta (transforming growth factor beta) , with 390-amino acid protein (about 43 kDa) , is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. In mammals, three isoforms of TGFbeta, that is, beta1, beta2, and beta3, are known. TGF beta is one of numerous inhibitory factors produced by cancer cells that regulate antitumor immunity. TGF beta1 takes part in the local response in the course of primary lung cancer and TGFbeta1 is thought to be implicated in breast cancer progression.TGFbeta1 also plays a critical role in the downregulation of microglial responses minimizing brain inflammation and thus avoiding exacerbation of brain damage.