Product Description
TRAIL-R3 Antibody [HS301] | 36-134 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: Recombinant human TRAIL-R3 (DcR1) .
Research Area: Cancer, Immunology
Tested Application: Flow, ICC
Application: Definition for 1 test: 1ul of labeled antibody in 200ul of Flow Cytometry buffer (see online protocol) .
Specificiy: Recognizes human TRAIL-R3. Does not cross-react with human TRAIL-R1, -R2 or -R4.
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: >95% (SDS-PAGE)
Clonality: Monoclonal
Clone: HS301
Isotype: IgG1
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
Concentration: 1 mg/ml
Storage Condition: Stable for at least 1 year after receipt when stored at -20˚C.
Alternate Name: TRAIL Receptor 3; DcR1; TRID; TNFRSF10C; CD263
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: TRAIL-R3 is a receptor for the cytotoxic ligand TRAIL. It lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. Protects cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.