Product Description
WDR77 Antibody [8B2F7] | 23-974 | ProSci
Host: Mouse
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant protein of human WDR77
Research Area: Signal Transduction
Tested Application: WB, ICC
Application: WB: 1:500 - 1:2000
ICC: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: K-562
Positive Control 2: HeLa
Positive Control 3: 293T
Positive Control 4: Jurkat
Positive Control 5: HepG2
Positive Control 6: MCF7
Molecular Weight: Observed: 39kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Monoclonal
Clone: [8B2F7]
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: WDR77, Androgen receptor cofactor p44, HKMT1069, MEP-50, Methylosome protein 50, p44, MEP50, Nbla10071, RP11-552M11.3, WD repeat domain 77
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The protein encoded by this gene is an androgen receptor coactivator that forms a complex with protein arginine methyltransferase 5, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. The encoded protein may be involved in the early stages of prostate cancer, with most of the protein being nuclear-localized in benign cells but cytoplasmic in cancer cells. Several transcript variants encoding different isoforms have been found for this gene.