Product Description
CD11c Antibody [3.9] | 99-467 | ProSci
Host: Mouse
Reactivity: Human, Rhesus, Cynomolgus
Homology: N/A
Immunogen: Rheumatoid synovial cells and human monocytes
Research Area: Immunology, Signal Transduction
Tested Application: IHC-Fr, Flow, IP, Costimulation, Activity
Application: CD11c Antibody [3.9] for use in flow cytometry, immunohistochemistry, immunoprecipitation, and blocking assays.
Specificiy: CD11c
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [3.9]
Isotype: IgG1
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration: 0.1 mg/mL
Storage Condition: Store vial at 2-8˚C
Alternate Name: Integrin alphaX, Axb2, CR4, p150, 95
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: CD11c is a 150 kDa adhesion glycoprotein that associates with beta2 integrin to form the CD11c/CD18 heterodimer that binds CD54 (ICAM-1) and fibrinogen. It is expressed on NK cells, a subset of B and T cells, granulocytes, monocytes, and macrophages. It functions in cytotoxic T cell killing and in neutrophil and monocyte adhesion to endothelium.