Product Description
CD45 Antibody [2D1] | 99-529 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: Human peripheral blood mononuclear cells
Research Area: Cancer, Immunology, Neuroscience, Signal Transduction
Tested Application: Flow
Application: CD45 Antibody [2D1] for use in flow cytometry, immunohistochemistry, western blotting, and immunoprecipitation assays.
Specificiy: CD45
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [2D1]
Isotype: IgG1
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration: 0.1 mg/mL
Storage Condition: Store vial at 2-8˚C
Alternate Name: LCA, T200, Ly5
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: CD45, also known as the leukocyte common antigen (LCA) , exists as four different isoforms (180, 190, 205, 220 kDa) that are generated by alternative splicing of three exons. LCA is found on all cells of hematopoietic origin, except erythrocytes and platelets. CD45 expression is required for T cell and B cell antigen receptor-mediated activation.