Euro
USD
British Pound
NULL
![CD51 Antibody [13C2]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/576336/814074/porsci_lo__79508.1648973713__13440.1649092177.png?c=2 "CD51 Antibody [13C2]")
![CD51 Antibody [13C2]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/576336/814074/porsci_lo__79508.1648973713__13440.1649092177.png?c=2 "CD51 Antibody [13C2]")
Product Description
CD51 Antibody [13C2] | 99-550 | ProSci
Host: Mouse
Reactivity: Human, African Green Monkey, Rabbit, Bovine
Homology: N/A
Immunogen: Cell suspension containing osteoclasts from osteoclastomas
Research Area: Other
Tested Application: Flow
Application: CD51 Antibody [13C2] for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, ELISA, purification, depletion, adhesion, and blocking assays.
Specificiy: CD51
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [13C2]
Isotype: IgG1
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration: 0.1 mg/mL
Storage Condition: Store vial at 2-8˚C
Alternate Name: Integrin alphaV, vitronectin receptor, VNR-alpha chain
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: CD51 represents the integrin alphaV chain that associates with integrin beta3 (CD61) to form the CD51/CD61 vitronectin receptor on endothelial cells, certain activated leukocytes, NK cells, macrophages, neutrophils, and platelets. CD51 is the most promiscuous integrin alpha subunit as it can form heterodimers with the beta1 (CD29) , beta3 (CD61) , beta5, beta6 and beta8 subunits in various tissues. CD51/CD61 acts as an activation-independent receptor for platelet attachment and spreading on vitronectin and other RGD-containing proteins including matrix components. It also mediates leukocyte-endothelial cell adhesion via interaction with CD31.
![CD51 Antibody [13C2]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/576336/814074/porsci_lo__79508.1648973713__13440.1649092177.png?c=2 "CD51 Antibody [13C2]")
![CD51 Antibody [13C2] (PE)](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/577206/815297/porsci_lo__79508.1648973713__06394.1649092338.png?c=2 "CD51 Antibody [13C2] (PE)")
![CD51 Antibody [13C2] (FITC)](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/577205/815296/porsci_lo__79508.1648973713__35538.1649092338.png?c=2 "CD51 Antibody [13C2] (FITC)")
