Product Description
CD95 Antibody [DX3] | 99-588 | ProSci
Host: Mouse
Reactivity: Human, Rat
Homology: N/A
Immunogen: Human CD95 transfected L cells
Research Area: Cancer, Cell Cycle, Immunology, Signal Transduction
Tested Application: Flow
Application: CD95 Antibody [DX3] for use in flow cytometry, ELISA, immunohistochemistry assays.
Specificiy: CD95
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [DX3]
Isotype: IgG2a
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Supplied in PBS
Concentration: 0.5 mg/mL
Storage Condition: Store vial at -20˚C
Alternate Name: APO-1, Fas, TNFRSF6
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: CD95, also known as Fas and APO-1, is a 45 kDa type I transmembrane glycoprotein and a member of the tumor necrosis factor receptor superfamily. It is expressed by activated lymphocytes, monocytes, neutrophils, fibroblasts, and cell lines. Fas ligand binding to CD95 induces apoptosis in activated mature lymphocytes thereby playing a role in maintaining peripheral tolerance.