Product Description
E-Cadherin Antibody [ECD1-2] | 34-050 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: A full length recombinant human protein was used as the immunogen for the E-Cadherin antibody.
Research Area: Cancer, Cell Cycle, Signal Transduction
Tested Application: IF, WB, IHC-P
Application: Western blot: 0.5-1 ug/ml
Immunohistochemistry (FFPE) : 1-2 ug/ml for 30 min at RT
Immunofluorescence: 0.5-1 ug/ml
Optimal dilution of the E-Cadherin antibody should be determined by the researcher.
Specificiy: Not suitable for Mouse, Rat sample testing
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Protein G affinity chromatography
Clonality: Monoclonal
Clone: ECD1-2
Isotype: IgG1, kappa
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration: 0.2 mg/mL
Storage Condition: Aliquot and Store at 2-8˚C. Avoid freez-thaw cycles.
Alternate Name: Cadherin-1, CAM 120/80, Epithelial cadherin, E-cadherin, Uvomorulin, CD324, E-Cad/CTF1, E-Cad/CTF2, E-Cad/CTF3, CDH1, CDHE, UVO
User Note: Optimal dilutions for each application to be determined by the researcher
BACKGROUND: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. [UniProt]