Euro
USD
British Pound
NULL
![Luteinizing Hormone alpha Antibody [LHa/756]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/575467/812224/porsci_lo__79508.1648973713__58213.1649091934.png?c=2 "Luteinizing Hormone alpha Antibody [LHa/756]")
![Luteinizing Hormone alpha Antibody [LHa/756]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/575467/812224/porsci_lo__79508.1648973713__58213.1649091934.png?c=2 "Luteinizing Hormone alpha Antibody [LHa/756]")
Product Description
Luteinizing Hormone alpha Antibody [LHa/756] | 33-645 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: Recombinant full-length human LHa protein was used as the immunogen for the Luteinizing Hormone alpha antibody.
Research Area: Cancer, Cell Cycle, Obesity, Neuroscience, Signal Transduction
Tested Application: IHC-P
Application: Immunohistochemistry (FFPE) : 1-2 ug/ml for 30 min RT
Optimal dilution of the Luteinizing Hormone alpha antibody should be determined by the researcher.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Protein G affinity chromatography
Clonality: Monoclonal
Clone: LHa/756
Isotype: IgG1, kappa
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration: 0.2 mg/mL
Storage Condition: Aliquot and Store at 2-8˚C. Avoid freez-thaw cycles.
Alternate Name: Glycoprotein hormones alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, Choriogonadotropin alpha chain, Chorionic gonadotrophin subunit alpha, CG-alpha, Follicle-stimulating hormone alpha chain, FSH-alpha, Follitropin alpha chain, Luteinizing hormone alpha chain, LSH-alpha, Lutropin alpha chain, Thyroid-stimulating hormone alpha chain, TSH-alpha, Thyrotropin alpha chain, CGA
User Note: Optimal dilutions for each application to be determined by the researcher
BACKGROUND: This mAb reacts with a protein of ~13kDa, identified as alpha subunit of Luteinizing Hormone (LH) or Chorionic Gonadotrophin (CG) . The protein dimer contains 2 polypeptide units, labeled alpha and beta subunits that are connected by two bridges. The alpha subunits of LH, FSH, TSH, and hCG are identical, and contain 92 amino acids. The beta subunits vary. LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action and is responsible for interaction with the LH receptor. This beta subunit contains the same amino acids in sequence as the beta subunit of hCG and both stimulate the same receptor; however, the hCG beta subunit contains an additional 24 amino acids and the hormones differ in the composition of their sugar moieties. LH is synthesized and secreted by gonadotrophs in the anterior lobe of the pituitary gland. In concert with the other pituitary gonadotropin follicle-stimulating hormone (FSH) , it is necessary for proper reproductive function. In the female, an acute rise of LH levels triggers ovulation. In the male, where LH has also been called Interstitial Cell-Stimulating Hormone (ICSH) , it stimulates Leydig cell production of testosterone. LH is a useful marker in classification of pituitary tumors and the study of pituitary disease.
![Luteinizing Hormone alpha Antibody [LHa/756]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/575467/812224/porsci_lo__79508.1648973713__58213.1649091934.png?c=2 "Luteinizing Hormone alpha Antibody [LHa/756]")
