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![MMP2 Antibody [MMP2/1501]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/575446/812174/porsci_lo__79508.1648973713__06471.1649091928.png?c=2 "MMP2 Antibody [MMP2/1501]")
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Product Description
MMP2 Antibody [MMP2/1501] | 33-619 | ProSci
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: Amino acids 195-319 were used as the immunogen for the MMP2 antibody.
Research Area: Cancer, Cell Cycle, Obesity
Tested Application: WB
Application: WB: 0.5-1 ug/ml
The stated application concentrations are suggested starting amounts. Titration of the MMP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Protein G affinity chromatography
Clonality: Monoclonal
Clone: MMP2/1501
Isotype: IgG1
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration: 0.2 mg/mL
Storage Condition: Aliquot and Store at 2-8˚C. Avoid freez-thaw cycles.
Alternate Name: 72 kDa type IV collagenase, 72 kDa gelatinase, Gelatinase A, Matrix metalloproteinase-2, MMP-2, TBE-1, PEX, MMP2, CLG4A
User Note: Optimal dilutions for each application to be determined by the researcher
BACKGROUND: It recognizes a protein of 72 kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB) . MMP catalysis requires both calcium and zinc. MMP2 (also designated type IV collagenase) cleaves collagen types IV, V, VII and X and gelatin type I. Activation of MMP2 secretion requires the Ras signaling pathway.
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