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Product Description
CAT Antibody, KO Validated | 18-205 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-225 of human CAT (NP_001743.1) .
Research Area: Cancer, Neuroscience, Signal Transduction
Tested Application: WB, IP
Application: WB: 1:1000 - 1:3000
IP: 1:20 - 1:50
Specificiy: N/A
Positive Control 1: HeLa
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 60kDa
Validation: Antibody is Knockout validated.
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: CAT, catalase, HGNC:1516, MGC138422, MGC138424,
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.
![[KO Validated] CAT Polyclonal Antibody](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/605286/857314/enogene__70285.1648844242__40038.1649167194.png?c=2 "[KO Validated] CAT Polyclonal Antibody")
![[KO Validated] CAT Polyclonal Antibody](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/295381/455518/sab-signalway-antibody__92073.1641690747__61989.1641691385.gif?c=2 "[KO Validated] CAT Polyclonal Antibody")
