Product Description
CREB (Ab 142) Antibody | 79-406 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: CREB (Ab-142) antibody was raised against a peptide sequence around aa.140~144 (D-L-S-S-D) derived from Human CREB.
Research Area: Neuroscience
Tested Application: IHC
Application: Immunohistochemistry: 1:50~1:100
Specificiy: This antibody detects endogenous level of total CREB protein.
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 43 kDa
Validation: N/A
Isoform: N/A
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality: Polyclonal
Clone: N/A
Isotype: N/A
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+) , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Condition: Store antibody at -20˚C for up to one year.
Alternate Name: CREB, ASH2L1, CREB-1, CREB1
User Note: N/A
BACKGROUND: This protein binds the cAMP response element (CRE) , a sequence present in many viral and cellular promoters. CREB stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Implicated in synchronization of circadian rhythmicity.