Product Description
GIPR Antibody | 23-919 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 22-138 of human GIPR (NP_000155.1) .
Research Area: Neuroscience, Signal Transduction
Tested Application: WB
Application: WB: 1:500 - 1:2000
Specificiy: N/A
Positive Control 1: K-562
Positive Control 2: Mouse liver
Positive Control 3: Rat heart
Positive Control 4: Rat brain
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 45kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: GIPR, MGC126722, HGNC:4271, gastric inhibitory polypeptide receptor, GIPR, PGQTL2
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP) , which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.