Product Description
HMGA2 Antibody | 14-608 | ProSci
Host: Rabbit
Reactivity: Human
Homology: N/A
Immunogen: A synthetic peptide of human HMGA2
Research Area: Cancer, Cell Cycle, Neuroscience, Stem Cell, Transcription
Tested Application: WB, Flow
Application: WB: 1:500 - 1:2000
Flow: 1:20 - 1:50
Specificiy: N/A
Positive Control 1: HepG2
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 17kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, pH7.3.
Concentration: N/A
Storage Condition: Store at 4˚C. Avoid freeze / thaw cycles.
Alternate Name: HMGA2, high mobility group AT-hook 2, BABL, HMGI-C, HMGIC, LIPO, STQTL9, High-mobility group protein HMGI-C, high-mobility group (nonhistone chromosomal) protein isoform I-C
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.