Product Description
RDH5 Antibody | 23-369 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-318 of human RDH5 (NP_002896.2) .
Research Area: Neuroscience
Tested Application: WB, IHC, IF
Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:100
IF: 1:50 - 1:100
Specificiy: N/A
Positive Control 1: A-549
Positive Control 2: BT-474
Positive Control 3: Mouse liver
Positive Control 4: Mouse kidney
Positive Control 5: Rat liver
Positive Control 6: N/A
Molecular Weight: Observed: 38kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: RDH5, short chain dehydrogenase/reductase family 9C, SDR9C5, retinol dehydrogenase 5 (11-cis/9-cis) , retinol dehydrogenase 5 (11-cis and 9-cis) , retinol dehydrogenase 1, RDH1, HSD17B9, FLJ97089, FLJ39337, 9-cis-retinol specific dehydrogenase, 11-cis RDH
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes an enzyme belonging to the short-chain dehydrogenases/reductases (SDR) family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S1 (biogenesis of lysosomal organelles complex-1, subunit 1) gene.