Product Description
SCNN1A Antibody | 63-651 | ProSci
Host: Rabbit
Reactivity: Human
Homology: N/A
Immunogen: This SCNN1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 365-391 amino acids from the Central region of human SCNN1A.
Research Area: Obesity, Neuroscience, Signal Transduction
Tested Application: WB, IHC-P, IF, Flow
Application: For WB starting dilution is: 1:2000
For FACS starting dilution is: 1:25
For IHC-P starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 76 kDa
Validation: N/A
Isoform: N/A
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality: Polyclonal
Clone: N/A
Isotype: Rabbit Ig
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: batch dependent
Storage Condition: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Alternate Name: Amiloride-sensitive sodium channel subunit alpha, Alpha-NaCH, Epithelial Na (+) channel subunit alpha, Alpha-ENaC, ENaCA, Nonvoltage-gated sodium channel 1 subunit alpha, SCNEA, SCNN1A, SCNN1
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been sociated with pseudohypoaldosteronism type 1 (PHA1) , a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids.