Product Description
TREM1 Antibody | 7185 | ProSci
Host: Rabbit
Reactivity: Human
Homology: Predicted species reactivity based on immunogen sequence: Mouse: (71%)
Immunogen: Rabbit polyclonal TREM1 antibody was raised against a 17 amino acid peptide near the amino terminus of human TREM1.
The immunogen is located within the first 50 amino acids of TREM1.
Research Area: Innate Immunity
Tested Application: E, WB
Application: TREM1 antibody can be used for detection of TREM1 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Specificiy: N/A
Positive Control 1: Cat. No. 1210 - HEK293 Cell Lysate
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Predicted: 26 kDa
Validation: N/A
Isoform: N/A
Purification: TREM1 Antibody is affinity chromatography purified via peptide column.
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: TREM1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Condition: TREM1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Alternate Name: TREM1 Antibody: CD354, TREM-1, Triggering receptor expressed on myeloid cells 1, Triggering receptor expressed on monocytes 1
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: TREM1 Antibody: TREM1 (triggering receptor expressed on myeloid cells 1) is a receptor belonging to the Ig superfamily that amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. It is thought that TREM1 other related TREM proteins such as TREM2 act to modulate the inflammatory response. TREM1 has also been linked to inflammatory bowel disease resulting in enhanced production of TNF, IL-6, IL-8, and MCP-1.