Product Description
EZR Antibody | 13-256 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 350-470 of human EZR (NP_003370.2) .
Research Area: Cancer, Cell Cycle, Immunology, Signal Transduction
Tested Application: WB, IHC, IF, IP
Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:100
IF: 1:50 - 1:100
IP: 1:50 - 1:100
Specificiy: N/A
Positive Control 1: M21
Positive Control 2: SW480
Positive Control 3: U-251MG
Positive Control 4: 293T
Positive Control 5: Mouse intestine
Positive Control 6: Mouse brain
Molecular Weight: Observed: 90kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: Ezrin, VIL2, villin 2 (ezrin) , CVIL, CVL, DKFZp762H157, FLJ26216, MGC1584, cytovillin, ezrin, villin 2
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.