Product Description
POLR3B Antibody | 14-569 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 680-900 of human POLR3B (NP_060552.4) .
Research Area: Other
Tested Application: WB
Application: WB: 1:1000 - 1:2000
Specificiy: N/A
Positive Control 1: MCF7
Positive Control 2: Mouse brain
Positive Control 3: Mouse spleen
Positive Control 4: Rat brain
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 128kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: POLR3B, FLJ10388, RPC2, C128, HLD8
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The largest subunit and the encoded protein form the catalytic center of RNA polymerase III. Mutations in this gene are a cause of hypomyelinating leukodystrophy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.