Product Description
PPAR gamma Antibody | 13-947 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 70-170 of human PPAR gamma (NP_056953.2) .
Research Area: Cell Cycle, Neuroscience, Obesity, Signal Transduction, Stem Cell, Transcription
Tested Application: WB, IHC
Application: WB: 1:500 - 1:1000IHC: 1:50 - 1:100
Specificiy: N/A
Positive Control 1: A-549
Positive Control 2: SKOV3
Positive Control 3: Mouse liver
Positive Control 4: Rat spleen
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 50kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: PPARG, GLM1, CIMT1, NR1C3, PPARG1, PPARG2, PPARgamma
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.