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Product Description
RHOC Antibody, KO Validated | 13-764 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-193 of human RHOC (NP_001036144.1) .
Research Area: Cancer, Cell Cycle, Signal Transduction
Tested Application: WB, IHC, IF
Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:100
IF: 1:50 - 1:100
Specificiy: N/A
Positive Control 1: U2OS
Positive Control 2: Jurkat
Positive Control 3: A-549
Positive Control 4: PC-12
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 22kDa
Validation: Antibody is Knockout validated.
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: RHOC, ARH9, ARHC, H9, MGC1448, MGC61427, RHOH9
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
![[KO Validated] RhoC Rabbit pAb](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/396324/574797/unnamed-776x1024__91681.1646254488__92229.1646256048__67547.1646652381.png?c=2 "[KO Validated] RhoC Rabbit pAb")
