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Product Description
GJB4 Antibody | 28-530 | ProSci
Host: Rabbit
Reactivity: Human
Homology: N/A
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GJB4.
Research Area: Membrane, Signal Transduction
Tested Application: E, WB
Application: GJB4 antibody can be used for detection of GJB4 by ELISA at 1:1562500. GJB4 antibody can be used for detection of GJB4 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.
Specificiy: N/A
Positive Control 1: Cat. No. 1205 - Jurkat Cell Lysate
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 29 kDa
Validation: N/A
Isoform: N/A
Purification: Antibody is purified by protein A chromatography method.
Clonality: Polyclonal
Clone: N/A
Isotype: N/A
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration: batch dependent
Storage Condition: For short periods of storage (days) store at 4˚C. For longer periods of storage, store GJB4 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Alternate Name: GJB4, EKV, CX30.3
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Connexins are homologous four-transmembrane-domain proteins and major components of gap junctions. The GJB4 gene encodes connexin 30.3 (Cx30.3) A mutation in connexin 30.3 is causally involved in erythrokeratodermia variabilis (EKV) , a mostly autosomal dominant disorder of keratinization.
