Product Description
RNF12 Antibody | 27-508 | ProSci
Host: Rabbit
Reactivity: Human, Dog
Homology: N/A
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RNF12.
Research Area: Transcription
Tested Application: E, WB, IHC
Application: RNF12 antibody can be used for detection of RNF12 by ELISA at 1:12500. RNF12 antibody can be used for detection of RNF12 by western blot at 2.0 μ/mL.
Specificiy: N/A
Positive Control 1: Cat. No. 1205 - Jurkat Cell Lysate
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 69 kDa
Validation: N/A
Isoform: N/A
Purification: Antibody is purified by peptide affinity chromatography method.
Clonality: Polyclonal
Clone: N/A
Isotype: N/A
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration: batch dependent
Storage Condition: For short periods of storage (days) store at 4˚C. For longer periods of storage, store RNF12 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Alternate Name: RNF12, RNF12, NY-REN-43
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: RNF12 is a RING-H2 zinc finger protein. It has been shown to be a ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM) , and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Alternatively spliced transcript variants encoding the same protein have been reported.