Product Description
SCNN1B Antibody | 28-219 | ProSci
Host: Rabbit
Reactivity: Human, Dog
Homology: N/A
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SCNN1B.
Research Area: Membrane, Signal Transduction
Tested Application: E, WB
Application: SCNN1B antibody can be used for detection of SCNN1B by ELISA at 1:312500. SCNN1B antibody can be used for detection of SCNN1B by western blot at 0.125 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.
Specificiy: N/A
Positive Control 1: Cat. No. 1205 - Jurkat Cell Lysate
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 70 kDa
Validation: N/A
Isoform: N/A
Purification: Antibody is purified by peptide affinity chromatography method.
Clonality: Polyclonal
Clone: N/A
Isotype: N/A
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration: batch dependent
Storage Condition: For short periods of storage (days) store at 4˚C. For longer periods of storage, store SCNN1B antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Alternate Name: SCNN1B, BESC1, ENaCb, SCNEB, ENaCbeta
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: When expressed in the bladder epithelium, the protein encoded by the SCNN1B gene might be implicated in the mechanosensory transduction in the bladder afferent pathways, thereby inducing detrusor instability by outlet obstruction. Common variants of this gene confer susceptibility to human essential hypertension.