Product Description
TRBP2 Antibody | 33-041 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Primate
Homology: N/A
Immunogen: A recombinant protein fragment within the C-terminal region of TRBP2 was used as the immunogen for this antibody.
Research Area: Other
Tested Application: WB
Application: Western blot: 5-10 ug/ml
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Protein A Affinity Chromatography
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration: 0.5 mg/mL
Storage Condition: Aliquot and Store at -20˚C. Avoid freez-thaw cycles.
Alternate Name: RISC-loading complex subunit TARBP2 {ECO:0000255|HAMAP-Rule:MF_03034}, TAR RNA-binding protein 2, Trans-activation-responsive RNA-binding protein, TARBP2 {ECO:0000255|HAMAP-Rule:MF_03034}, TRBP
User Note: Optimal dilutions for each application to be determined by the researcher
BACKGROUND: TRBP2 (TAR (HIV-1) RNA binding protein 2) , along with Dicer and Argonaute-2, is part of the RISC (RNA induced silencing complex) . As part of the RISC, TRBP2 is important in viral defense. Dicer cleaves dsRNA into siRNA. Through TRBP2-Dicer interaction, the siRNA template is loaded onto Argonaute-2, which cleaves encountered viral mRNA strands complementary to the loaded siRNA base-pair sequence.