Product Description
IL31RA Antibody | 22-026 | ProSci
Host: Rabbit
Reactivity: Human, Mouse
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human IL31RA (NP_001229568.1) .
Research Area: Apoptosis, Cell Cycle, Chemokines & Cytokines, Immunology, Innate Immunity, Signal Transduction
Tested Application: WB
Application: WB: 1:500 - 1:2000
Specificiy: N/A
Positive Control 1: Mouse liver
Positive Control 2: Mouse heart
Positive Control 3: Mouse brain
Positive Control 4: Mouse pancreas
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 83kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: CRL, CRL3, GLM-R, GLMR, GPL, IL-31RA, PLCA2, PRO21384, hGLM-R, interleukin-31 receptor subunit alpha, IL-31 receptor subunit alpha, IL-31R subunit alpha, class I cytokine receptor, cytokine receptor-like 3, gp130-like monocyte receptor, soluble type I cytokine receptor CRL3, zcytoR17
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The protein encoded by this gene belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR) . Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.