Product Description
BP-1 Antibody [FG35.4] (FITC) | 98-887 | ProSci
Host: Rat
Reactivity: Mouse
Homology: N/A
Immunogen: N/A
Research Area: Obesity
Tested Application: WB, IHC-P, IHC-Fr, ICC, Flow, Blocking, IP, Activity
Application: BP-1 Antibody [FG35.4] for use in flow cytometry assays.
Specificiy: BP-1
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [FG35.4]
Isotype: IgG1
Conjugate: FITC
Physical State: Liquid
Buffer: Supplied in PBS/NaN3
Concentration: 0.5 mg/mL
Storage Condition: Store vial at 2-8˚C
Alternate Name: Ly-51, 6C3, aminopeptidase A, glutamyl aminopeptidase
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: BP-1, also known as Ly-51 and 6C3 antigen, is a type II homodimeric transmembrane glycoprotein formed by two disulfide-linked chains of 140 kDa. Originally identified on the surface of pre-B cell lymphomas the cDNA encoding BP-1 has been cloned and found to represent aminopeptidase A. It is expressed at high levels on bone marrow stromal cell lines which support in vitro B lymphopoiesis and on a wide variety of mouse tissues known to possess aminopeptidase activity. Subsets of normal bone marrow pre-B and B cells express low levels of BP-1 which is rapidly upregulated on pre-B cells in the presence of IL-7. The BP-1 marker is commonly used to identify B cells in different stages of development.