Product Description
CD117 Antibody [ACK2] | 76-895 | ProSci
Host: Rat
Reactivity: Mouse
Homology: N/A
Immunogen: N/A
Research Area: Cancer, Functional Assays
Tested Application: Flow, Func, IHC, ICC, WB
Application: N/A
Specificiy: The ACK2 monoclonal antibody specifically reacts with mouse CD117 (c-Kit receptor) , a 145 kDa transmembrane tyrosine-kinase receptor encoded by the Kit gene.
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality: Monoclonal
Clone: ACK2
Isotype: Rat IgG2b, kappa
Conjugate: Unconjugated
Physical State: liquid
Buffer: Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration: batch dependent
Storage Condition: The product should be stored undiluted at 4˚C and should be protected from prolonged exposure to light. Do not freeze.
Alternate Name: W, Bs, Fdc, Ssm, SCO1, SCO5, SOW3, CD117, c-KIT, Tr-kit, Gsfsco1, Gsfsco5, Gsfsow3, Kit
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The ACK2 monoclonal antibody specifically reacts with mouse CD117 (c-Kit receptor) , a 145 kDa transmembrane tyrosine-kinase receptor encoded by the Kit gene. The c-Kit receptor, also known as stem cell factor receptor, is expressed on hematopoietic progenitor cells in adult bone marrow, in progenitors of erythroid and myeloid lineages, and precursors of B and T cells. CD117 enhances the proliferation and the differentiation of the hematopoietic progenitor cells and seems to enhance the development of T cells, as the c-Kit receptor and its ligand are expressed by the thymus.