Product Description
CD41 Antibody [MWReg30] | 76-170 | ProSci
Host: Rat
Reactivity: Mouse
Homology: N/A
Immunogen: N/A
Research Area: Stem Cell
Tested Application: Flow, Func
Application: N/A
Specificiy: The MWReg30 monoclonal antibody specifically reacts with mouse CD41, a transmembrane glycoprotein also known as integrin alpha 2b GPIIb.
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Clonality: Monoclonal
Clone: MWReg30
Isotype: Rat IgG1, kappa
Conjugate: Unconjugated
Physical State: liquid
Buffer: Phosphate-buffered aqueous solution, ph7.2.
Concentration: batch dependent
Storage Condition: The product should be stored undiluted at 4˚C . Do not freeze.
Alternate Name: CD41, CD41B, GpIIb, AI172977, alphaIIb, Itga2b
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The MWReg30 monoclonal antibody specifically reacts with mouse CD41, a transmembrane glycoprotein also known as integrin alpha 2b GPIIb. It is expressed on hematopoietic progenitors, megakaryocytes, and platelets. It forms a receptor with CD61 (integrin beta 3) that binds adhesion molecules such as fibrinogen, fibronectin, von Willebrand factor, and thrombin. Defects or absence of CD41 has been found to lead to coagulation disorders. The expression profile of CD150+, CD48-, and CD41- can be used to identify hematopoietic stem cells.