Product Description
CD49d Antibody [R1-2] | 76-810 | ProSci
Host: Rat
Reactivity: mouse
Homology: N/A
Immunogen: N/A
Research Area: Immunology, Functional Assays
Tested Application: Flow, Func
Application: N/A
Specificiy: The R1-2 monoclonal antibody specifically reacts with mouse CD49d (integrin alpha 4) , which forms the VLA-4 complex with CD29 (integrin beta 1) .
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Clonality: Monoclonal
Clone: R1-2
Isotype: Rat IgG2b, kappa
Conjugate: Unconjugated
Physical State: liquid
Buffer: Phosphate-buffered aqueous solution, ph7.2.
Concentration: batch dependent
Storage Condition: The product should be stored undiluted at 4˚C . Do not freeze.
Alternate Name: CD49D, Itga4B, Itga4
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The R1-2 monoclonal antibody specifically reacts with mouse CD49d (integrin alpha 4) , which forms the VLA-4 complex with CD29 (integrin beta 1) . VLA-4 is expressed on thymocytes, monocytes, and a subset of peripheral lymphocytes. It is the receptor for fibronectin and CD106 (VCAM-1) . CD49d also forms a receptor for mucosal vascular addressin (MAdCAM-1) with integrin beta 7.