Product Description
CD49e Antibody [5H10.27] | 98-811 | ProSci
Host: Rat
Reactivity: Mouse
Homology: N/A
Immunogen: C57BL/6 x A/J F1 mouse mast cell line MC/9
Research Area: Cancer, Signal Transduction
Tested Application: Flow
Application: CD49e Antibody [5H10.27] for use in flow cytometry, immunohistochemistry, costimulation, blocking, and adhesion assays.
Specificiy: CD49e
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [5H10.27]
Isotype: IgG2a
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Supplied in PBS
Concentration: 0.5 mg/mL
Storage Condition: Store vial at -20˚C
Alternate Name: Integrin alpha5, VLA-5alpha
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The monoclonal antibody 5H10.27 reacts with the alpha5 chain (VLA-5) of the CD49e/CD29 heterodimeric fibronectin receptor. It is expressed on thymocytes, activated T cells, mast cells, and a variety of mouse cell lines. Soluble 5H10.27 antibody inhibits VLA-5-mediated functions in vitro. Immobilized 5H10.27 has also been demonstrated to costimulate the proliferative response of CD8+ T cells to plate-bound anti-CD3 monoclonal antibody.