Product Description
SOX17 Antibody | 7917 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: SOX17 antibody was raised against a 16 amino acid peptide near the center of human SOX17.
The immunogen is located within amino acids 240 - 290 of SOX17.
Research Area: Stem Cell
Tested Application: E, WB, IF
Application: SOX17 antibody can be used for detection of SOX17 by Western blot at 0.5 - 1 μg/ml. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Specificiy: SOX17 antibody is human, mouse and rat reactive. SOX17 is predicted to not cross-react with other SOX proteins.
Positive Control 1: Cat. No. 1211 - HepG2 Cell Lysate
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Predicted: 46 kDa
Observed: 42 kDa
Validation: N/A
Isoform: N/A
Purification: SOX17 antibody is affinity chromatography purified via peptide column.
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: SOX17 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Condition: SOX17 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Alternate Name: SOX17 Antibody: VUR3, Transcription factor SOX-17
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: SOX17 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate (1, 2) . SOX17 is part of the SoxF subgroup which plays an important role in the differentiation of different cell types, including visceral and definitive endoderm and hematopoietic cell types (3, 4) . SOX17 is also essential for acquisition and maintenance of arterial identity (5) .