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Product Description
SOX18 Antibody | 7919 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: SOX18 antibody was raised against a 17 amino acid peptide near the amino terminus of human SOX18.
The immunogen is located within amino acids 40 - 90 of SOX18.
Research Area: Stem Cell
Tested Application: E, WB
Application: SOX18 antibody can be used for detection of SOX18 by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.
Specificiy: SOX18 antibody is human, mouse and rat reactive. SOX18 is predicted to not cross-react with other SOX proteins.
Positive Control 1: Cat. No. 1212 - 3T3 Cell Lysate
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Predicted: 42 kDa
Observed: 44 kDa
Validation: N/A
Isoform: N/A
Purification: SOX18 antibody is affinity chromatography purified via peptide column.
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: SOX18 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Condition: SOX18 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Alternate Name: SOX18 Antibody: HLTS, Transcription factor SOX-18
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: SOX18 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate (1, 2) . SOX18 is part of the SoxF subgroup which plays an important role in the differentiation of different cell types (3) . SOX is known to be involved with vascularization and endothelial development, suggesting that it may be useful as a potential target for inhibiting tumor angiogenesis (4) . Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia (5) .
